Annexon Inc ANNX Stock Analysis
- Nasdaq
- Stock
- Market closed · opens Monday 9:30 AM ET
$4.20 up $0.20, 4.87% at close Nov 6
Last close · Previous close $4.01
- Market cap
- $688.14MAt the Nov 6 close
- P/E ratio
- n/mLoss over last 12 months
- Diluted EPS
- −$1.14Last 12 months
- Dividend yield
- NoneLast 12 months
Price chart
$4.20up $0.20, 4.87%Fri, Nov 6 session
Use the left and right arrow keys to move along the chart.
Price data
Trading
- Previous close$4.01Nov 5
- Volume2.62MNov 6 session
Shares traded on all US exchanges in the last completed session. Live intraday volume covers IEX only, so it is left out.
- Avg. volume3.68MLast 21 sessions
The average daily shares traded over the last 21 trading sessions, about one calendar month.
- 52-week range: $2.54 to $7.18; now $4.20
The lowest and highest trades over the past 52 weeks, adjusted for splits. The marker shows the latest price.
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Performance
Past performance, measured to the Nov 6 close. Total return includes reinvested dividends.Price change only, without dividends. Compared with the S&P 500, using SPY.
ANNX beat the S&P 500 in 3 of 6 periods.
| Period | ANNX and S&P 500 | vs S&P 500 |
|---|---|---|
| Short term | ||
| 1M | ANNX: up 4.2% S&P 500: down 5.6% | ANNX beat the S&P 500 by 9.8 percentage points Beat |
| 3M | ANNX: down 25.0% S&P 500: down 4.1% | ANNX trailed the S&P 500 by 20.9 percentage points Trailed |
| YTD | ANNX: down 16.3% S&P 500: up 8.7% | ANNX trailed the S&P 500 by 25.0 percentage points Trailed |
| 1Y | ANNX: up 39.1% S&P 500: up 10.9% | ANNX beat the S&P 500 by 28.2 percentage points Beat |
| Long term | ||
| 3Y | ANNX: up 90.9% S&P 500: up 75.0% +24.1% vs +20.5% a year | ANNX beat the S&P 500 by 15.9 percentage points Beat |
| 5Y | ANNX: down 72.9% S&P 500: up 67.8% −23.0% vs +10.9% a year | ANNX trailed the S&P 500 by 140.7 percentage points Trailed |
$10,000 invested in ANNX 5 years ago (Nov 5, 2021) would be worth about $2,708 at the close on , with dividends reinvested. The same amount in the S&P 500 would be worth about $16,782.
ANNX beat the S&P 500 in 3 of 6 periods.
| Period | ANNX and S&P 500 | vs S&P 500 |
|---|---|---|
| Short term | ||
| 1M | ANNX: up 4.2% S&P 500: down 5.6% | ANNX beat the S&P 500 by 9.8 percentage points Beat |
| 3M | ANNX: down 25.0% S&P 500: down 4.3% | ANNX trailed the S&P 500 by 20.7 percentage points Trailed |
| YTD | ANNX: down 16.3% S&P 500: up 7.8% | ANNX trailed the S&P 500 by 24.1 percentage points Trailed |
| 1Y | ANNX: up 39.1% S&P 500: up 9.7% | ANNX beat the S&P 500 by 29.4 percentage points Beat |
| Long term | ||
| 3Y | ANNX: up 90.9% S&P 500: up 68.8% +24.1% vs +19.1% a year | ANNX beat the S&P 500 by 22.1 percentage points Beat |
| 5Y | ANNX: down 72.9% S&P 500: up 56.9% −23.0% vs +9.4% a year | ANNX trailed the S&P 500 by 129.8 percentage points Trailed |
$10,000 invested in ANNX 5 years ago (Nov 5, 2021) would be worth about $2,708 at the close on , not counting dividends. The same amount in the S&P 500 would be worth about $15,694.
All-time high
$35.01
Closing high on . Now 88.0% below that record.
Split-adjusted daily closes since Jul 24, 2020.
Stock splits
ANNX hasn’t split since its price history begins in 2020.
Valuation
The Nov 6 close compared with the last 12 months of reported results (the four quarters to Jun 30, 2026). Tap a metric to see how it’s calculated.
Price-to-earnings (P/E)
n/mDiluted EPS of −$1.14 over the last 12 months
A P/E ratio isn’t meaningful while earnings over the last 12 months are negative. How to read P/E
Other valuation measures
- 3.7×Book value as of Jun 30, 2026
Price relative to accounting equity (book value) per share on the Jun 30, 2026 balance sheet. Asset-light companies often trade far above book value.
P/B = Price ÷ Book value per sharePrice-to-book ratio - −28.08%Last 12 months’ free cash flow
Free cash flow over the last 12 months as a share of the company’s market value: the cash the business generated for each dollar of stock.
FCF yield = Free cash flow (last 12 months) ÷ Market capFree cash flow - $502.51MAt the Nov 6 close
What it would cost to buy the whole business: the market cap at the Nov 6 close, plus debt, minus cash and short-term investments from the Jun 30, 2026 balance sheet.
EV = Market cap + Debt − Cash and short-term investmentsEV/EBITDA explained
Build your own ANNX DCF in Excel. Value Annexon with your own growth and margin assumptions.Browse DCF models Free DCF calculator
Financials
Reported results, not forecasts. From company filings via Tiingo; the latest report is Q2 FY26, the quarter ended Jun 30, 2026. “Last 12 months” means the four quarters from Jul 1, 2025 to Jun 30, 2026, and balance-sheet figures are as of Jun 30, 2026.
Revenue and net income
Last 12 months, with the change from the 12 months before
- Revenue
- $0.00
- Net income
- −$202.67M
- Diluted EPS
- −$1.14
Data table
| Period | Revenue | Net income | Diluted EPS |
|---|---|---|---|
| Q3 FY24 (Sep 30, 2024) | $0.00 | −$34.82M | −$0.25 |
| Q4 FY24 (Dec 31, 2024) | $0.00 | −$48.59M | −$0.33 |
| Q1 FY25 (Mar 31, 2025) | $0.00 | −$54.36M | −$0.37 |
| Q2 FY25 (Jun 30, 2025) | $0.00 | −$49.16M | −$0.34 |
| Q3 FY25 (Sep 30, 2025) | $0.00 | −$54.92M | −$0.37 |
| Q4 FY25 (Dec 31, 2025) | $0.00 | −$48.26M | −$0.26 |
| Q1 FY26 (Mar 31, 2026) | $0.00 | −$44.14M | −$0.23 |
| Q2 FY26 (Jun 30, 2026) | $0.00 | −$55.35M | −$0.28 |
| Period | Revenue | Net income | Diluted EPS |
|---|---|---|---|
| FY21 (Dec 31, 2021) | $0.00 | −$130.32M | −$3.40 |
| FY22 (Dec 31, 2022) | $0.00 | −$141.95M | −$2.60 |
| FY23 (Dec 31, 2023) | $0.00 | −$134.24M | −$1.77 |
| FY24 (Dec 31, 2024) | $0.00 | −$138.20M | −$1.01 |
| FY25 (Dec 31, 2025) | $0.00 | −$206.69M | −$1.34 |
Margins
- Gross —
- Operating —
- Net —
The percentages above the chart cover the last 12 months; the lines show each quarter. What margins tell you
Cash flow
- −$193.22MLast 12 months
Cash from operations minus capital spending: the cash left after the business maintains and grows its assets.
FCF = Operating cash flow − Capital spendingFree cash flow - Operating cash flow−$193.03MLast 12 months
- Capital spending$185.00KLast 12 months
Shareholder returns
- $177.28MLast 12 months
Cash spent repurchasing shares, net of shares issued. Buybacks shrink the share count, so each remaining share owns more of the company.
- Dividends paid$0.00Last 12 months
- Total returned$0.00Last 12 months
Balance sheet
- $210.28MAs of Jun 30, 2026
Cash plus short- and long-term marketable securities on the Jun 30, 2026 balance sheet.
- Total debt$24.65MAs of Jun 30, 2026
- Net cash$185.62MAs of Jun 30, 2026
- 5.53As of Jun 30, 2026
Current assets divided by current liabilities on the Jun 30, 2026 balance sheet. Above 1 means short-term assets cover the bills due within a year.
Current ratio = Current assets ÷ Current liabilitiesCurrent ratio - 0.13As of Jun 30, 2026
Total debt divided by shareholders’ equity on the Jun 30, 2026 balance sheet: a measure of financial leverage.
D/E = Total debt ÷ Shareholders’ equityDebt-to-equity ratio
Financial strength
- −106.2%Last 12 months
Over the last 12 months, Annexon lost money: its net loss was 106.2% of its shareholders’ equity (averaged over the last four quarter-ends). It describes the past year, not an expected return.
ROE = Net income (last 12 months) ÷ Average equityReturn on equity - −79.8%Last 12 months
Over the last 12 months, Annexon’s net loss was 79.8% of its total assets (averaged over the last four quarter-ends).
ROA = Net income (last 12 months) ÷ Average total assets
About Annexon Inc
Annexon is a clinical-stage biopharmaceutical company developing a new class of complement medicines for patients with classical complement-mediated autoimmune, neurodegenerative and ophthalmic disorders of the body, brain and eye. The company’s pipeline is based on its platform technology addressing a broad spectrum of well-researched classical complement-mediated autoimmune and neurodegenerative diseases triggered by aberrant activation of C1q, the initiating molecule of the classical complement pathway. Annexon is advancing a portfolio of innovative product candidates designed to block the activity of C1q and the entire classical complement pathway: ANX005 (intravenous administration), ANX007 (intravitreal administration) and ANX009 (subcutaneous administration). Annexon is deploying a disciplined, biomarker-driven strategy designed to improve the probability of technical success of its portfolio.
- Sector
- Healthcare
- Industry
- Biotechnology
- Headquarters
- California, USA
- SEC filings
- EDGAR (opens in a new tab)
- Exchange
- Nasdaq
- Asset type
- Common stock
- Price history since
ANNX news
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ANNX stock FAQ
What is ANNX stock’s price today?
Annexon (ANNX) traded at $4.20 at the close on , up $0.20 (4.87%) from the previous close of $4.01. Over the past 52 weeks it has traded between $2.54 and $7.18.
If you invested $1,000 in ANNX 5 years ago, how much would you have now?
With dividends reinvested, $1,000 invested in ANNX on would be worth about $271 at the close on , a total return of −72.9%. The same $1,000 would be worth $1,391 if invested one year ago. Past performance doesn’t predict future returns.
What is Annexon’s market cap?
Annexon’s market capitalization is about $688.1 million. That’s Tiingo’s daily market cap for , at that day’s closing price of $4.20 (how market cap works). Annexon reported 163.84M shares outstanding at the end of its latest quarter ().
What is ANNX’s P/E ratio?
ANNX’s P/E ratio isn’t meaningful right now because its earnings over the four quarters to are negative (diluted EPS of −$1.14).
What are ANNX’s earnings per share?
ANNX’s diluted earnings per share were −$1.14 over the four quarters to , compared with −$1.29 in the twelve months before. The latest quarter (Q2 FY26) brought −$0.28 per share, against −$0.34 a year earlier (how EPS works).
Does ANNX pay a dividend?
Annexon hasn’t paid a dividend in the last twelve months.
What is ANNX’s 52-week high and low?
Over the past 52 weeks ANNX has traded as low as $2.54 and as high as $7.18. At $4.20 at the close on , it is 41.5% below that high and 65.4% above the low.
What is ANNX’s all-time high?
ANNX’s highest closing price was $35.01 on , adjusted for stock splits. At $4.20 at the close on , it is 88.0% below that record.
Has ANNX stock ever split?
No. ANNX hasn’t split since its price history begins in 2020.
How has ANNX stock performed?
Including dividends and measured to the close on , ANNX has returned −16.3% so far this year and +39.1% over the past year, and −72.9% over five years (−23.0% a year). Over the same periods the S&P 500, measured by SPY, returned +8.7%, +10.9% and +67.8%. Past performance doesn’t predict future returns.
What sector and industry is Annexon in?
Annexon is in the Healthcare sector and the Biotechnology industry, and is headquartered in California, USA.
What exchange does ANNX trade on?
Annexon trades on the Nasdaq under the ticker symbol ANNX. Its price history on this dashboard begins on .
Member SIPC.Low CommissionsLearn More (opens in a new tab)Sponsored. Affiliate link: I may earn a commission. The inclusion of Interactive Brokers’ (IBKR) name, logo or weblink is present pursuant to an advertising arrangement only. IBKR is not a contributor, reviewer, provider or sponsor of content published on this site, and is not responsible for the accuracy of any products or services discussed.
About this data. Data sourced by Tiingo (opens in a new tab). The live price is Tiingo’s real-time price, based on IEX trades and quotes; intraday charts show IEX trades, and volume figures are consolidated totals for completed sessions. Prices are split-adjusted, and total returns assume dividends are reinvested. Financials come from company filings and can lag new reports. Times are Eastern.
This page is for education, not investment advice. Past performance doesn't predict future returns. Logos provided by Logo.dev (opens in a new tab).
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