Axsome Therapeutics Inc AXSM Stock Analysis
- Nasdaq
- Stock
- Market closed · opens Monday 9:30 AM ET
$132.37 up $2.57, 1.98% at close Nov 6
Last close · Previous close $129.80
- Market cap
- $6.93BAt the Nov 6 close
- P/E ratio
- n/mLoss over last 12 months
- Diluted EPS
- −$3.05Last 12 months
- Dividend yield
- NoneLast 12 months
Price chart
$132.37up $2.57, 1.98%Fri, Nov 6 session
Use the left and right arrow keys to move along the chart.
Price data
Trading
- Previous close$129.80Nov 5
- Volume718.40KNov 6 session
Shares traded on all US exchanges in the last completed session. Live intraday volume covers IEX only, so it is left out.
- Avg. volume1.09MLast 21 sessions
The average daily shares traded over the last 21 trading sessions, about one calendar month.
- 52-week range: $123.00 to $260.19; now $132.37
The lowest and highest trades over the past 52 weeks, adjusted for splits. The marker shows the latest price.
Member SIPC.Low CommissionsLearn More (opens in a new tab)Sponsored. Affiliate link: I may earn a commission. The inclusion of Interactive Brokers’ (IBKR) name, logo or weblink is present pursuant to an advertising arrangement only. IBKR is not a contributor, reviewer, provider or sponsor of content published on this site, and is not responsible for the accuracy of any products or services discussed.
Performance
Past performance, measured to the Nov 6 close. Total return includes reinvested dividends.Price change only, without dividends. Compared with the S&P 500, using SPY.
AXSM beat the S&P 500 in 3 of 7 periods.
| Period | AXSM and S&P 500 | vs S&P 500 |
|---|---|---|
| Short term | ||
| 1M | AXSM: down 24.1% S&P 500: down 5.6% | AXSM trailed the S&P 500 by 18.5 percentage points Trailed |
| 3M | AXSM: down 37.0% S&P 500: down 4.1% | AXSM trailed the S&P 500 by 32.9 percentage points Trailed |
| YTD | AXSM: down 27.5% S&P 500: up 8.7% | AXSM trailed the S&P 500 by 36.2 percentage points Trailed |
| 1Y | AXSM: down 5.0% S&P 500: up 10.9% | AXSM trailed the S&P 500 by 15.9 percentage points Trailed |
| Long term | ||
| 3Y | AXSM: up 112.1% S&P 500: up 75.0% +28.5% vs +20.5% a year | AXSM beat the S&P 500 by 37.1 percentage points Beat |
| 5Y | AXSM: up 229.3% S&P 500: up 67.8% +26.9% vs +10.9% a year | AXSM beat the S&P 500 by 161.5 percentage points Beat |
| 10Y | AXSM: up 1,984.6% S&P 500: up 313.1% +35.5% vs +15.2% a year | AXSM beat the S&P 500 by 1,671.5 percentage points Beat |
$10,000 invested in AXSM 10 years ago (Nov 4, 2016) would be worth about $208,457 at the close on , with dividends reinvested. The same amount in the S&P 500 would be worth about $41,313.
AXSM beat the S&P 500 in 3 of 7 periods.
| Period | AXSM and S&P 500 | vs S&P 500 |
|---|---|---|
| Short term | ||
| 1M | AXSM: down 24.1% S&P 500: down 5.6% | AXSM trailed the S&P 500 by 18.5 percentage points Trailed |
| 3M | AXSM: down 37.0% S&P 500: down 4.3% | AXSM trailed the S&P 500 by 32.7 percentage points Trailed |
| YTD | AXSM: down 27.5% S&P 500: up 7.8% | AXSM trailed the S&P 500 by 35.3 percentage points Trailed |
| 1Y | AXSM: down 5.0% S&P 500: up 9.7% | AXSM trailed the S&P 500 by 14.7 percentage points Trailed |
| Long term | ||
| 3Y | AXSM: up 112.1% S&P 500: up 68.8% +28.5% vs +19.1% a year | AXSM beat the S&P 500 by 43.3 percentage points Beat |
| 5Y | AXSM: up 229.3% S&P 500: up 56.9% +26.9% vs +9.4% a year | AXSM beat the S&P 500 by 172.4 percentage points Beat |
| 10Y | AXSM: up 1,984.6% S&P 500: up 252.6% +35.5% vs +13.4% a year | AXSM beat the S&P 500 by 1,732.0 percentage points Beat |
$10,000 invested in AXSM 10 years ago (Nov 4, 2016) would be worth about $208,457 at the close on , not counting dividends. The same amount in the S&P 500 would be worth about $35,257.
All-time high
$255.17
Closing high on . Now 48.1% below that record.
Split-adjusted daily closes since Nov 19, 2015.
Stock splits
AXSM hasn’t split since its price history begins in 2015.
Valuation
The Nov 6 close compared with the last 12 months of reported results (the four quarters to Sep 30, 2026). Tap a metric to see how it’s calculated.
Price-to-earnings (P/E)
n/mDiluted EPS of −$3.05 over the last 12 months
A P/E ratio isn’t meaningful while earnings over the last 12 months are negative. How to read P/E
Other valuation measures
- 8.0×Last 12 months’ revenue
Market value divided by revenue over the last 12 months. Useful when earnings are small or negative.
P/S = Market cap ÷ Revenue (last 12 months)Price-to-sales ratio - 65.8×Book value as of Sep 30, 2026
Price relative to accounting equity (book value) per share on the Sep 30, 2026 balance sheet. Asset-light companies often trade far above book value.
P/B = Price ÷ Book value per sharePrice-to-book ratio - −1.19%Last 12 months’ free cash flow
Free cash flow over the last 12 months as a share of the company’s market value: the cash the business generated for each dollar of stock.
FCF yield = Free cash flow (last 12 months) ÷ Market capFree cash flow - $6.84BAt the Nov 6 close
What it would cost to buy the whole business: the market cap at the Nov 6 close, plus debt, minus cash and short-term investments from the Sep 30, 2026 balance sheet.
EV = Market cap + Debt − Cash and short-term investmentsEV/EBITDA explained
Build your own AXSM DCF in Excel. Value Axsome Therapeutics with your own growth and margin assumptions.Browse DCF models Free DCF calculator
Financials
Reported results, not forecasts. From company filings via Tiingo; the latest report is Q3 FY26, the quarter ended Sep 30, 2026. “Last 12 months” means the four quarters from Oct 1, 2025 to Sep 30, 2026, and balance-sheet figures are as of Sep 30, 2026.
Revenue and net income
Last 12 months, with the change from the 12 months before
- Revenue
- $865.27Mup 54.2%
- Net income
- −$157.29M
- Diluted EPS
- −$3.05
Data table
| Period | Revenue | Net income | Diluted EPS |
|---|---|---|---|
| Q4 FY24 (Dec 31, 2024) | $118.77M | −$74.91M | −$1.54 |
| Q1 FY25 (Mar 31, 2025) | $121.46M | −$59.41M | −$1.22 |
| Q2 FY25 (Jun 30, 2025) | $150.04M | −$47.97M | −$0.97 |
| Q3 FY25 (Sep 30, 2025) | $170.99M | −$47.23M | −$0.94 |
| Q4 FY25 (Dec 31, 2025) | $196.00M | −$28.56M | −$0.55 |
| Q1 FY26 (Mar 31, 2026) | $191.20M | −$64.54M | −$1.26 |
| Q2 FY26 (Jun 30, 2026) | $218.38M | −$51.31M | −$0.99 |
| Q3 FY26 (Sep 30, 2026) | $259.69M | −$12.88M | −$0.25 |
| Period | Revenue | Net income | Diluted EPS |
|---|---|---|---|
| FY21 (Dec 31, 2021) | $0.00 | −$130.40M | −$3.47 |
| FY22 (Dec 31, 2022) | $50.04M | −$187.13M | −$4.60 |
| FY23 (Dec 31, 2023) | $270.60M | −$239.24M | −$5.27 |
| FY24 (Dec 31, 2024) | $385.69M | −$287.22M | −$5.99 |
| FY25 (Dec 31, 2025) | $638.50M | −$183.17M | −$3.68 |
Margins
- Gross 93.2%
- Operating −17.5%
- Net −18.2%
The percentages above the chart cover the last 12 months; the lines show each quarter. What margins tell you
Cash flow
- −$82.61MLast 12 months
Cash from operations minus capital spending: the cash left after the business maintains and grows its assets.
FCF = Operating cash flow − Capital spendingFree cash flow - Operating cash flow−$81.77MLast 12 months
- Capital spending$839.00KLast 12 months
- −9.5%Last 12 months
Free cash flow as a share of revenue, both over the last 12 months.
Shareholder returns
- $102.84MLast 12 months
Cash spent repurchasing shares, net of shares issued. Buybacks shrink the share count, so each remaining share owns more of the company.
- Dividends paid$0.00Last 12 months
- Total returned$0.00Last 12 months
Balance sheet
- $313.86MAs of Sep 30, 2026
Cash plus short- and long-term marketable securities on the Sep 30, 2026 balance sheet.
- Total debt$218.67MAs of Sep 30, 2026
- Net cash$95.19MAs of Sep 30, 2026
- 1.42As of Sep 30, 2026
Current assets divided by current liabilities on the Sep 30, 2026 balance sheet. Above 1 means short-term assets cover the bills due within a year.
Current ratio = Current assets ÷ Current liabilitiesCurrent ratio - 2.07As of Sep 30, 2026
Total debt divided by shareholders’ equity on the Sep 30, 2026 balance sheet: a measure of financial leverage.
D/E = Total debt ÷ Shareholders’ equityDebt-to-equity ratio
Financial strength
- 5 of 9Last 12 months
vs the 12 beforeA 0–9 checklist from accounting professor Joseph Piotroski. Each test compares the last 12 months with the 12 months before and scores a point if it passes. 8–9 is strong; 0–2 is weak.
- ✗Net income was positive: not passed
- ✗Operating cash flow was positive: not passed
- ✓Return on assets improved: passed
- ✓Operating cash flow exceeded net income: passed
- ✓Long-term debt fell relative to assets: passed
- ✗Current ratio improved: not passed
- ✗Share count didn’t rise: not passed
- ✓Gross margin improved: passed
- ✓Asset turnover (revenue ÷ assets) improved: passed
- −189.7%Last 12 months
Over the last 12 months, Axsome Therapeutics lost money: its net loss was 189.7% of its shareholders’ equity (averaged over the last four quarter-ends). It describes the past year, not an expected return.
ROE = Net income (last 12 months) ÷ Average equityReturn on equity - −21.0%Last 12 months
Over the last 12 months, Axsome Therapeutics’s net loss was 21.0% of its total assets (averaged over the last four quarter-ends).
ROA = Net income (last 12 months) ÷ Average total assets
About Axsome Therapeutics Inc
Axsome Therapeutics is a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) conditions. We deliver scientific breakthroughs by identifying critical gaps in care and develop differentiated products with a focus on novel mechanisms of action that enable meaningful advancements in patient outcomes. Our industry-leading neuroscience portfolio includes FDA-approved treatments for major depressive disorder and excessive daytime sleepiness associated with narcolepsy and obstructive sleep apnea and multiple late-stage development programs addressing a broad range of serious neurological and psychiatric conditions that impact over 150 million people in the United States. Together, we are on a mission to solve some of the brain’s biggest problems so patients and their loved ones can flourish.
- Sector
- Healthcare
- Industry
- Biotechnology
- Headquarters
- New York, USA
- SEC filings
- EDGAR (opens in a new tab)
- Exchange
- Nasdaq
- Asset type
- Common stock
- Price history since
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AXSM stock FAQ
What is AXSM stock’s price today?
Axsome Therapeutics (AXSM) traded at $132.37 at the close on , up $2.57 (1.98%) from the previous close of $129.80. Over the past 52 weeks it has traded between $123.00 and $260.19.
If you invested $1,000 in AXSM 10 years ago, how much would you have now?
With dividends reinvested, $1,000 invested in AXSM on would be worth about $20,846 at the close on , a total return of +1,984.6%. The same $1,000 would be worth $3,293 if invested five years ago and $950 if invested one year ago. Past performance doesn’t predict future returns.
What is Axsome Therapeutics’s market cap?
Axsome Therapeutics’s market capitalization is about $6.9 billion. That’s Tiingo’s daily market cap for , at that day’s closing price of $132.37 (how market cap works). Axsome Therapeutics reported 52.38M shares outstanding at the end of its latest quarter ().
What is AXSM’s P/E ratio?
AXSM’s P/E ratio isn’t meaningful right now because its earnings over the four quarters to are negative (diluted EPS of −$3.05).
How much revenue does Axsome Therapeutics make?
Axsome Therapeutics reported $865.3 million of revenue over the four quarters to , up 54.2% from the twelve months before. In its latest quarter (Q3 FY26, ended ) revenue was $259.7 million, up 51.9% from a year earlier.
Is Axsome Therapeutics profitable?
Not over the four quarters to . Axsome Therapeutics reported a net loss of $157.3 million across those four quarters on $865.3 million of revenue.
What are AXSM’s earnings per share?
AXSM’s diluted earnings per share were −$3.05 over the four quarters to , compared with −$4.67 in the twelve months before. The latest quarter (Q3 FY26) brought −$0.25 per share, against −$0.94 a year earlier (how EPS works).
Does AXSM pay a dividend?
Axsome Therapeutics hasn’t paid a dividend in the last twelve months.
What is AXSM’s 52-week high and low?
Over the past 52 weeks AXSM has traded as low as $123.00 and as high as $260.19. At $132.37 at the close on , it is 49.1% below that high and 7.6% above the low.
What is AXSM’s all-time high?
AXSM’s highest closing price was $255.17 on , adjusted for stock splits. At $132.37 at the close on , it is 48.1% below that record.
Has AXSM stock ever split?
No. AXSM hasn’t split since its price history begins in 2015.
How has AXSM stock performed?
Including dividends and measured to the close on , AXSM has returned −27.5% so far this year and −5.0% over the past year, and +229.3% over five years (+26.9% a year). Over the same periods the S&P 500, measured by SPY, returned +8.7%, +10.9% and +67.8%. Past performance doesn’t predict future returns.
What sector and industry is Axsome Therapeutics in?
Axsome Therapeutics is in the Healthcare sector and the Biotechnology industry, and is headquartered in New York, USA.
What exchange does AXSM trade on?
Axsome Therapeutics trades on the Nasdaq under the ticker symbol AXSM. Its price history on this dashboard begins on .
Member SIPC.Low CommissionsLearn More (opens in a new tab)Sponsored. Affiliate link: I may earn a commission. The inclusion of Interactive Brokers’ (IBKR) name, logo or weblink is present pursuant to an advertising arrangement only. IBKR is not a contributor, reviewer, provider or sponsor of content published on this site, and is not responsible for the accuracy of any products or services discussed.
About this data. Data sourced by Tiingo (opens in a new tab). The live price is Tiingo’s real-time price, based on IEX trades and quotes; intraday charts show IEX trades, and volume figures are consolidated totals for completed sessions. Prices are split-adjusted, and total returns assume dividends are reinvested. Financials come from company filings and can lag new reports. Times are Eastern.
This page is for education, not investment advice. Past performance doesn't predict future returns. Logos provided by Logo.dev (opens in a new tab).
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