Nautilus Biotechnology Inc NAUT Stock Analysis
- Nasdaq
- Stock
- Market closed · opens Monday 9:30 AM ET
$2.23 up $0.08, 3.72% at close Nov 6
Last close · Previous close $2.15
- Market cap
- $283.78MAt the Nov 6 close
- P/E ratio
- n/mLoss over last 12 months
- Diluted EPS
- −$0.46Last 12 months
- Dividend yield
- NoneLast 12 months
Price chart
$2.23up $0.08, 3.72%Fri, Nov 6 session
Use the left and right arrow keys to move along the chart.
Price data
Trading
- Previous close$2.15Nov 5
- Volume4.55MNov 6 session
Shares traded on all US exchanges in the last completed session. Live intraday volume covers IEX only, so it is left out.
- Avg. volume10.33MLast 21 sessions
The average daily shares traded over the last 21 trading sessions, about one calendar month.
- 52-week range: $0.84 to $4.31; now $2.23
The lowest and highest trades over the past 52 weeks, adjusted for splits. The marker shows the latest price.
Member SIPC.Low CommissionsLearn More (opens in a new tab)Sponsored. Affiliate link: I may earn a commission. The inclusion of Interactive Brokers’ (IBKR) name, logo or weblink is present pursuant to an advertising arrangement only. IBKR is not a contributor, reviewer, provider or sponsor of content published on this site, and is not responsible for the accuracy of any products or services discussed.
Performance
Past performance, measured to the Nov 6 close. Total return includes reinvested dividends.Price change only, without dividends. Compared with the S&P 500, using SPY.
NAUT beat the S&P 500 in 4 of 6 periods.
| Period | NAUT and S&P 500 | vs S&P 500 |
|---|---|---|
| Short term | ||
| 1M | NAUT: up 26.0% S&P 500: down 5.6% | NAUT beat the S&P 500 by 31.6 percentage points Beat |
| 3M | NAUT: up 151.7% S&P 500: down 4.1% | NAUT beat the S&P 500 by 155.8 percentage points Beat |
| YTD | NAUT: up 14.4% S&P 500: up 8.7% | NAUT beat the S&P 500 by 5.7 percentage points Beat |
| 1Y | NAUT: up 47.7% S&P 500: up 10.9% | NAUT beat the S&P 500 by 36.8 percentage points Beat |
| Long term | ||
| 3Y | NAUT: down 9.0% S&P 500: up 75.0% −3.1% vs +20.5% a year | NAUT trailed the S&P 500 by 84.0 percentage points Trailed |
| 5Y | NAUT: down 60.2% S&P 500: up 67.8% −16.8% vs +10.9% a year | NAUT trailed the S&P 500 by 128.0 percentage points Trailed |
$10,000 invested in NAUT 5 years ago (Nov 5, 2021) would be worth about $3,982 at the close on , with dividends reinvested. The same amount in the S&P 500 would be worth about $16,782.
NAUT beat the S&P 500 in 4 of 6 periods.
| Period | NAUT and S&P 500 | vs S&P 500 |
|---|---|---|
| Short term | ||
| 1M | NAUT: up 26.0% S&P 500: down 5.6% | NAUT beat the S&P 500 by 31.6 percentage points Beat |
| 3M | NAUT: up 151.7% S&P 500: down 4.3% | NAUT beat the S&P 500 by 156.0 percentage points Beat |
| YTD | NAUT: up 14.4% S&P 500: up 7.8% | NAUT beat the S&P 500 by 6.6 percentage points Beat |
| 1Y | NAUT: up 47.7% S&P 500: up 9.7% | NAUT beat the S&P 500 by 38.0 percentage points Beat |
| Long term | ||
| 3Y | NAUT: down 9.0% S&P 500: up 68.8% −3.1% vs +19.1% a year | NAUT trailed the S&P 500 by 77.8 percentage points Trailed |
| 5Y | NAUT: down 60.2% S&P 500: up 56.9% −16.8% vs +9.4% a year | NAUT trailed the S&P 500 by 117.1 percentage points Trailed |
$10,000 invested in NAUT 5 years ago (Nov 5, 2021) would be worth about $3,982 at the close on , not counting dividends. The same amount in the S&P 500 would be worth about $15,694.
All-time high
$11.00
Closing high on . Now 79.7% below that record.
Split-adjusted daily closes since Jun 10, 2021.
Stock splits
NAUT hasn’t split since its price history begins in 2021.
Valuation
The Nov 6 close compared with the last 12 months of reported results (the four quarters to Sep 30, 2026). Tap a metric to see how it’s calculated.
Price-to-earnings (P/E)
n/mDiluted EPS of −$0.46 over the last 12 months
A P/E ratio isn’t meaningful while earnings over the last 12 months are negative. How to read P/E
Other valuation measures
- 669.3×Last 12 months’ revenue
Market value divided by revenue over the last 12 months. Useful when earnings are small or negative.
P/S = Market cap ÷ Revenue (last 12 months)Price-to-sales ratio - 2.4×Book value as of Sep 30, 2026
Price relative to accounting equity (book value) per share on the Sep 30, 2026 balance sheet. Asset-light companies often trade far above book value.
P/B = Price ÷ Book value per sharePrice-to-book ratio - −19.43%Last 12 months’ free cash flow
Free cash flow over the last 12 months as a share of the company’s market value: the cash the business generated for each dollar of stock.
FCF yield = Free cash flow (last 12 months) ÷ Market capFree cash flow - $223.94MAt the Nov 6 close
What it would cost to buy the whole business: the market cap at the Nov 6 close, plus debt, minus cash and short-term investments from the Sep 30, 2026 balance sheet.
EV = Market cap + Debt − Cash and short-term investmentsEV/EBITDA explained
Build your own NAUT DCF in Excel. Value Nautilus Biotechnology with your own growth and margin assumptions.Browse DCF models Free DCF calculator
Financials
Reported results, not forecasts. From company filings via Tiingo; the latest report is Q3 FY26, the quarter ended Sep 30, 2026. “Last 12 months” means the four quarters from Oct 1, 2025 to Sep 30, 2026, and balance-sheet figures are as of Sep 30, 2026.
Revenue and net income
Last 12 months, with the change from the 12 months before
- Revenue
- $424.00K
- Net income
- −$58.58M
- Diluted EPS
- −$0.46
Data table
| Period | Revenue | Net income | Diluted EPS |
|---|---|---|---|
| Q4 FY24 (Dec 31, 2024) | $0.00 | −$17.59M | −$0.14 |
| Q1 FY25 (Mar 31, 2025) | $0.00 | −$16.61M | −$0.13 |
| Q2 FY25 (Jun 30, 2025) | $0.00 | −$15.03M | −$0.12 |
| Q3 FY25 (Sep 30, 2025) | $0.00 | −$13.57M | −$0.11 |
| Q4 FY25 (Dec 31, 2025) | $0.00 | −$13.78M | −$0.11 |
| Q1 FY26 (Mar 31, 2026) | $0.00 | −$14.70M | −$0.12 |
| Q2 FY26 (Jun 30, 2026) | $190.00K | −$14.47M | −$0.11 |
| Q3 FY26 (Sep 30, 2026) | $234.00K | −$15.64M | −$0.12 |
| Period | Revenue | Net income | Diluted EPS |
|---|---|---|---|
| FY21 (Dec 31, 2021) | $0.00 | −$50.32M | −$0.60 |
| FY22 (Dec 31, 2022) | $0.00 | −$57.92M | −$0.46 |
| FY23 (Dec 31, 2023) | $0.00 | −$63.68M | −$0.51 |
| FY24 (Dec 31, 2024) | $0.00 | −$70.78M | −$0.56 |
| FY25 (Dec 31, 2025) | $0.00 | −$59.00M | −$0.47 |
Margins
- Gross 90.8%
- Operating −15,105.7%
- Net −13,816.7%
The percentages above the chart cover the last 12 months; the lines show each quarter. What margins tell you
Cash flow
- −$55.14MLast 12 months
Cash from operations minus capital spending: the cash left after the business maintains and grows its assets.
FCF = Operating cash flow − Capital spendingFree cash flow - Operating cash flow−$52.48MLast 12 months
- Capital spending$2.65MLast 12 months
- −13,003.5%Last 12 months
Free cash flow as a share of revenue, both over the last 12 months.
Shareholder returns
- $1.48MLast 12 months
Cash spent repurchasing shares, net of shares issued. Buybacks shrink the share count, so each remaining share owns more of the company.
- Dividends paid$0.00Last 12 months
- Total returned$0.00Last 12 months
Balance sheet
- $114.34MAs of Sep 30, 2026
Cash plus short- and long-term marketable securities on the Sep 30, 2026 balance sheet.
- Total debt$26.74MAs of Sep 30, 2026
- Net cash$87.60MAs of Sep 30, 2026
- 9.25As of Sep 30, 2026
Current assets divided by current liabilities on the Sep 30, 2026 balance sheet. Above 1 means short-term assets cover the bills due within a year.
Current ratio = Current assets ÷ Current liabilitiesCurrent ratio - 0.23As of Sep 30, 2026
Total debt divided by shareholders’ equity on the Sep 30, 2026 balance sheet: a measure of financial leverage.
D/E = Total debt ÷ Shareholders’ equityDebt-to-equity ratio
Financial strength
- −42.7%Last 12 months
Over the last 12 months, Nautilus Biotechnology lost money: its net loss was 42.7% of its shareholders’ equity (averaged over the last four quarter-ends). It describes the past year, not an expected return.
ROE = Net income (last 12 months) ÷ Average equityReturn on equity - −34.4%Last 12 months
Over the last 12 months, Nautilus Biotechnology’s net loss was 34.4% of its total assets (averaged over the last four quarter-ends).
ROA = Net income (last 12 months) ÷ Average total assets
About Nautilus Biotechnology Inc
With its corporate headquarters in Seattle and its research and development headquarters in the San Francisco Bay Area, Nautilus is a development stage life sciences company creating a platform technology for quantifying and unlocking the complexity of the proteome. Nautilus’ mission is to transform the field of proteomics by democratizing access to the proteome and enabling fundamental advancements across human health and medicine. To learn more about Nautilus, visit www.nautilus.bio.
- Sector
- Healthcare
- Industry
- Biotechnology
- Headquarters
- Washington, USA
- SEC filings
- EDGAR (opens in a new tab)
- Exchange
- Nasdaq
- Asset type
- Common stock
- Price history since
NAUT news
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NAUT stock FAQ
What is NAUT stock’s price today?
Nautilus Biotechnology (NAUT) traded at $2.23 at the close on , up $0.08 (3.72%) from the previous close of $2.15. Over the past 52 weeks it has traded between $0.84 and $4.31.
If you invested $1,000 in NAUT 5 years ago, how much would you have now?
With dividends reinvested, $1,000 invested in NAUT on would be worth about $398 at the close on , a total return of −60.2%. The same $1,000 would be worth $1,477 if invested one year ago. Past performance doesn’t predict future returns.
What is Nautilus Biotechnology’s market cap?
Nautilus Biotechnology’s market capitalization is about $283.8 million. That’s Tiingo’s daily market cap for , at that day’s closing price of $2.23 (how market cap works). Nautilus Biotechnology reported 127.26M shares outstanding at the end of its latest quarter ().
What is NAUT’s P/E ratio?
NAUT’s P/E ratio isn’t meaningful right now because its earnings over the four quarters to are negative (diluted EPS of −$0.46).
How much revenue does Nautilus Biotechnology make?
Nautilus Biotechnology reported $424.0 thousand of revenue over the four quarters to . In its latest quarter (Q3 FY26, ended ) revenue was $234.0 thousand.
Is Nautilus Biotechnology profitable?
Not over the four quarters to . Nautilus Biotechnology reported a net loss of $58.6 million across those four quarters on $424.0 thousand of revenue.
What are NAUT’s earnings per share?
NAUT’s diluted earnings per share were −$0.46 over the four quarters to , compared with −$0.50 in the twelve months before. The latest quarter (Q3 FY26) brought −$0.12 per share, against −$0.11 a year earlier (how EPS works).
Does NAUT pay a dividend?
Nautilus Biotechnology hasn’t paid a dividend in the last twelve months.
What is NAUT’s 52-week high and low?
Over the past 52 weeks NAUT has traded as low as $0.84 and as high as $4.31. At $2.23 at the close on , it is 48.3% below that high and 165.1% above the low.
What is NAUT’s all-time high?
NAUT’s highest closing price was $11.00 on , adjusted for stock splits. At $2.23 at the close on , it is 79.7% below that record.
Has NAUT stock ever split?
No. NAUT hasn’t split since its price history begins in 2021.
How has NAUT stock performed?
Including dividends and measured to the close on , NAUT has returned +14.4% so far this year and +47.7% over the past year, and −60.2% over five years (−16.8% a year). Over the same periods the S&P 500, measured by SPY, returned +8.7%, +10.9% and +67.8%. Past performance doesn’t predict future returns.
What sector and industry is Nautilus Biotechnology in?
Nautilus Biotechnology is in the Healthcare sector and the Biotechnology industry, and is headquartered in Washington, USA.
What exchange does NAUT trade on?
Nautilus Biotechnology trades on the Nasdaq under the ticker symbol NAUT. Its price history on this dashboard begins on .
Member SIPC.Low CommissionsLearn More (opens in a new tab)Sponsored. Affiliate link: I may earn a commission. The inclusion of Interactive Brokers’ (IBKR) name, logo or weblink is present pursuant to an advertising arrangement only. IBKR is not a contributor, reviewer, provider or sponsor of content published on this site, and is not responsible for the accuracy of any products or services discussed.
About this data. Data sourced by Tiingo (opens in a new tab). The live price is Tiingo’s real-time price, based on IEX trades and quotes; intraday charts show IEX trades, and volume figures are consolidated totals for completed sessions. Prices are split-adjusted, and total returns assume dividends are reinvested. Financials come from company filings and can lag new reports. Times are Eastern.
This page is for education, not investment advice. Past performance doesn't predict future returns. Logos provided by Logo.dev (opens in a new tab).
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