Talphera Inc TLPH Stock Analysis
- Nasdaq
- Stock
- Market closed · opens Monday 9:30 AM ET
$1.05 up $0.04, 3.96% at close Nov 6
Last close · Previous close $1.01
- Market cap
- $54.49MAt the Nov 6 close
- P/E ratio
- n/mLoss over last 12 months
- Diluted EPS
- −$0.24Last 12 months
- Dividend yield
- NoneLast 12 months
Price chart
$1.05down $0.06, 5.41%Past month
Use the left and right arrow keys to move along the chart.
Price data
Trading
- Previous close$1.01Nov 5
- Volume79.42KNov 6 session
Shares traded on all US exchanges in the last completed session. Live intraday volume covers IEX only, so it is left out.
- Avg. volume54.99KLast 21 sessions
The average daily shares traded over the last 21 trading sessions, about one calendar month.
- 52-week range: $0.69 to $1.57; now $1.05
The lowest and highest trades over the past 52 weeks, adjusted for splits. The marker shows the latest price.
Member SIPC.Low CommissionsLearn More (opens in a new tab)Sponsored. Affiliate link: I may earn a commission. The inclusion of Interactive Brokers’ (IBKR) name, logo or weblink is present pursuant to an advertising arrangement only. IBKR is not a contributor, reviewer, provider or sponsor of content published on this site, and is not responsible for the accuracy of any products or services discussed.
Performance
Past performance, measured to the Nov 6 close. Total return includes reinvested dividends.Price change only, without dividends. Compared with the S&P 500, using SPY.
TLPH beat the S&P 500 in 2 of 7 periods.
| Period | TLPH and S&P 500 | vs S&P 500 |
|---|---|---|
| Short term | ||
| 1M | TLPH: down 5.4% S&P 500: down 5.6% | TLPH beat the S&P 500 by 0.2 percentage points Beat |
| 3M | TLPH: down 26.6% S&P 500: down 4.1% | TLPH trailed the S&P 500 by 22.5 percentage points Trailed |
| YTD | TLPH: down 7.9% S&P 500: up 8.7% | TLPH trailed the S&P 500 by 16.6 percentage points Trailed |
| 1Y | TLPH: down 9.5% S&P 500: up 10.9% | TLPH trailed the S&P 500 by 20.4 percentage points Trailed |
| Long term | ||
| 3Y | TLPH: up 110.0% S&P 500: up 75.0% +28.0% vs +20.5% a year | TLPH beat the S&P 500 by 35.0 percentage points Beat |
| 5Y | TLPH: down 93.9% S&P 500: up 67.8% −42.8% vs +10.9% a year | TLPH trailed the S&P 500 by 161.7 percentage points Trailed |
| 10Y | TLPH: down 98.0% S&P 500: up 313.1% −32.3% vs +15.2% a year | TLPH trailed the S&P 500 by 411.1 percentage points Trailed |
$10,000 invested in TLPH 10 years ago (Nov 4, 2016) would be worth about $202 at the close on , with dividends reinvested. The same amount in the S&P 500 would be worth about $41,313.
TLPH beat the S&P 500 in 2 of 7 periods.
| Period | TLPH and S&P 500 | vs S&P 500 |
|---|---|---|
| Short term | ||
| 1M | TLPH: down 5.4% S&P 500: down 5.6% | TLPH beat the S&P 500 by 0.2 percentage points Beat |
| 3M | TLPH: down 26.6% S&P 500: down 4.3% | TLPH trailed the S&P 500 by 22.3 percentage points Trailed |
| YTD | TLPH: down 7.9% S&P 500: up 7.8% | TLPH trailed the S&P 500 by 15.7 percentage points Trailed |
| 1Y | TLPH: down 9.5% S&P 500: up 9.7% | TLPH trailed the S&P 500 by 19.2 percentage points Trailed |
| Long term | ||
| 3Y | TLPH: up 110.0% S&P 500: up 68.8% +28.0% vs +19.1% a year | TLPH beat the S&P 500 by 41.2 percentage points Beat |
| 5Y | TLPH: down 93.9% S&P 500: up 56.9% −42.8% vs +9.4% a year | TLPH trailed the S&P 500 by 150.8 percentage points Trailed |
| 10Y | TLPH: down 98.0% S&P 500: up 252.6% −32.3% vs +13.4% a year | TLPH trailed the S&P 500 by 350.6 percentage points Trailed |
$10,000 invested in TLPH 10 years ago (Nov 4, 2016) would be worth about $202 at the close on , not counting dividends. The same amount in the S&P 500 would be worth about $35,257.
All-time high
$262.40
Closing high on . Now 99.6% below that record.
Split-adjusted daily closes since Feb 11, 2011.
Stock splits
1
1-for-20 on . Share counts adjust after each split.
Valuation
The Nov 6 close compared with the last 12 months of reported results (the four quarters to Jun 30, 2026). Tap a metric to see how it’s calculated.
Price-to-earnings (P/E)
n/mDiluted EPS of −$0.24 over the last 12 months
A P/E ratio isn’t meaningful while earnings over the last 12 months are negative. When TLPH was profitable over the past five years, its P/E ranged from 0.1× to 1.4×, with a median of 0.4×. How to read P/E
Other valuation measures
- 54,494.6×Last 12 months’ revenue
Market value divided by revenue over the last 12 months. Useful when earnings are small or negative.
P/S = Market cap ÷ Revenue (last 12 months)Price-to-sales ratio - 3.8×Book value as of Jun 30, 2026
Price relative to accounting equity (book value) per share on the Jun 30, 2026 balance sheet. Asset-light companies often trade far above book value.
P/B = Price ÷ Book value per sharePrice-to-book ratio - −22.52%Last 12 months’ free cash flow
Free cash flow over the last 12 months as a share of the company’s market value: the cash the business generated for each dollar of stock.
FCF yield = Free cash flow (last 12 months) ÷ Market capFree cash flow - $43.92MAt the Nov 6 close
What it would cost to buy the whole business: the market cap at the Nov 6 close, plus debt, minus cash and short-term investments from the Jun 30, 2026 balance sheet.
EV = Market cap + Debt − Cash and short-term investmentsEV/EBITDA explained
Build your own TLPH DCF in Excel. Value Talphera with your own growth and margin assumptions.Browse DCF models Free DCF calculator
Financials
Reported results, not forecasts. From company filings via Tiingo; the latest report is Q2 FY26, the quarter ended Jun 30, 2026. “Last 12 months” means the four quarters from Jul 1, 2025 to Jun 30, 2026, and balance-sheet figures are as of Jun 30, 2026.
Revenue and net income
Last 12 months, with the change from the 12 months before
- Revenue
- $1.00Kdown 96.3%
- Net income
- −$15.08M
- Diluted EPS
- −$0.24
Data table
| Period | Revenue | Net income | Diluted EPS |
|---|---|---|---|
| Q3 FY24 (Sep 30, 2024) | $0.00 | −$3.35M | −$0.13 |
| Q4 FY24 (Dec 31, 2024) | $0.00 | −$1.87M | −$0.07 |
| Q1 FY25 (Mar 31, 2025) | $27.00K | −$2.59M | −$0.10 |
| Q2 FY25 (Jun 30, 2025) | $0.00 | −$3.49M | −$0.10 |
| Q3 FY25 (Sep 30, 2025) | $1.00K | −$4.44M | −$0.11 |
| Q4 FY25 (Dec 31, 2025) | $0.00 | −$3.77M | −$0.03 |
| Q1 FY26 (Mar 31, 2026) | $0.00 | −$2.56M | −$0.04 |
| Q2 FY26 (Jun 30, 2026) | $0.00 | −$4.31M | −$0.06 |
| Period | Revenue | Net income | Diluted EPS |
|---|---|---|---|
| FY21 (Dec 31, 2021) | $2.82M | −$35.10M | Paused See the note under the price. |
| FY22 (Dec 31, 2022) | $0.00 | $47.76M | $5.72 |
| FY23 (Dec 31, 2023) | $651.00K | −$18.40M | −$1.29 |
| FY24 (Dec 31, 2024) | $0.00 | −$13.00M | −$0.50 |
| FY25 (Dec 31, 2025) | $28.00K | −$14.29M | −$0.34 |
Margins
- Gross 100.0%
- Operating −1,474,700.0%
- Net −1,507,600.0%
The percentages above the chart cover the last 12 months; the lines show each quarter. What margins tell you
Cash flow
- −$12.27MLast 12 months
Cash from operations minus capital spending: the cash left after the business maintains and grows its assets.
FCF = Operating cash flow − Capital spendingFree cash flow - Operating cash flow−$12.27MLast 12 months
- Capital spending$0.00Last 12 months
- −1,227,000.0%Last 12 months
Free cash flow as a share of revenue, both over the last 12 months.
Shareholder returns
- $22.18MLast 12 months
Cash spent repurchasing shares, net of shares issued. Buybacks shrink the share count, so each remaining share owns more of the company.
- Dividends paid$0.00Last 12 months
- Total returned$0.00Last 12 months
Balance sheet
- $17.08MAs of Jun 30, 2026
Cash plus short- and long-term marketable securities on the Jun 30, 2026 balance sheet.
- Total debt$6.50MAs of Jun 30, 2026
- Net cash$10.58MAs of Jun 30, 2026
- 4.29As of Jun 30, 2026
Current assets divided by current liabilities on the Jun 30, 2026 balance sheet. Above 1 means short-term assets cover the bills due within a year.
Current ratio = Current assets ÷ Current liabilitiesCurrent ratio - 0.45As of Jun 30, 2026
Total debt divided by shareholders’ equity on the Jun 30, 2026 balance sheet: a measure of financial leverage.
D/E = Total debt ÷ Shareholders’ equityDebt-to-equity ratio
Financial strength
- 3 of 9Last 12 months
vs the 12 beforeA 0–9 checklist from accounting professor Joseph Piotroski. Each test compares the last 12 months with the 12 months before and scores a point if it passes. 8–9 is strong; 0–2 is weak.
- ✗Net income was positive: not passed
- ✗Operating cash flow was positive: not passed
- ✗Return on assets improved: not passed
- ✓Operating cash flow exceeded net income: passed
- ✓Long-term debt fell relative to assets: passed
- ✓Current ratio improved: passed
- ✗Share count didn’t rise: not passed
- ✗Gross margin improved: not passed
- ✗Asset turnover (revenue ÷ assets) improved: not passed
- −87.3%Last 12 months
Over the last 12 months, Talphera lost money: its net loss was 87.3% of its shareholders’ equity (averaged over the last four quarter-ends). It describes the past year, not an expected return.
ROE = Net income (last 12 months) ÷ Average equityReturn on equity - −51.4%Last 12 months
Over the last 12 months, Talphera’s net loss was 51.4% of its total assets (averaged over the last four quarter-ends).
ROA = Net income (last 12 months) ÷ Average total assets
About Talphera Inc
Talphera, Inc. is a specialty pharmaceutical company focused on the development and commercialization of innovative therapies for use in medically supervised settings. Talphera's lead product candidate, Niyad® is a lyophilized formulation of nafamostat and is currently being studied under an investigational device exemption (IDE) as an anticoagulant for the extracorporeal circuit. Nafamostat has received Breakthrough Device Designation status from the U.S. Food and Drug Administration (FDA). This release is intended for investors only.
- Sector
- Healthcare
- Industry
- Drug Manufacturers - Specialty & Generic
- Headquarters
- California, USA
- SEC filings
- EDGAR (opens in a new tab)
- Exchange
- Nasdaq
- Asset type
- Common stock
- Price history since
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TLPH stock FAQ
What is TLPH stock’s price today?
Talphera (TLPH) traded at $1.05 at the close on , up $0.04 (3.96%) from the previous close of $1.01. Over the past 52 weeks it has traded between $0.69 and $1.57.
If you invested $1,000 in TLPH 10 years ago, how much would you have now?
With dividends reinvested, $1,000 invested in TLPH on would be worth about $20 at the close on , a total return of −98.0%. The same $1,000 would be worth $61 if invested five years ago and $905 if invested one year ago. Past performance doesn’t predict future returns.
What is Talphera’s market cap?
Talphera’s market capitalization is about $54.5 million. That’s Tiingo’s daily market cap for , at that day’s closing price of $1.05 (how market cap works). Talphera reported 51.90M shares outstanding at the end of its latest quarter ().
What is TLPH’s P/E ratio?
TLPH’s P/E ratio isn’t meaningful right now because its earnings over the four quarters to are negative (diluted EPS of −$0.24). When it was profitable over the past five years, its P/E ranged from 0.1 to 1.4.
How much revenue does Talphera make?
Talphera reported $1.0 thousand of revenue over the four quarters to , down 96.3% from the twelve months before. In its latest quarter (Q2 FY26, ended ) revenue was $0.0 thousand.
Is Talphera profitable?
Not over the four quarters to . Talphera reported a net loss of $15.1 million across those four quarters on $1.0 thousand of revenue.
What are TLPH’s earnings per share?
TLPH’s diluted earnings per share were −$0.24 over the four quarters to , compared with −$0.40 in the twelve months before. The latest quarter (Q2 FY26) brought −$0.06 per share, against −$0.10 a year earlier (how EPS works).
Does TLPH pay a dividend?
Talphera hasn’t paid a dividend in the last twelve months.
What is TLPH’s 52-week high and low?
Over the past 52 weeks TLPH has traded as low as $0.69 and as high as $1.57. At $1.05 at the close on , it is 33.1% below that high and 52.9% above the low.
What is TLPH’s all-time high?
TLPH’s highest closing price was $262.40 on , adjusted for stock splits. At $1.05 at the close on , it is 99.6% below that record.
Has TLPH stock ever split?
Yes, once: 1-for-20 on .
How has TLPH stock performed?
Including dividends and measured to the close on , TLPH has returned −7.9% so far this year and −9.5% over the past year, and −93.9% over five years (−42.8% a year). Over the same periods the S&P 500, measured by SPY, returned +8.7%, +10.9% and +67.8%. Past performance doesn’t predict future returns.
What sector and industry is Talphera in?
Talphera is in the Healthcare sector and the Drug Manufacturers - Specialty & Generic industry, and is headquartered in California, USA.
What exchange does TLPH trade on?
Talphera trades on the Nasdaq under the ticker symbol TLPH. Its price history on this dashboard begins on .
Member SIPC.Low CommissionsLearn More (opens in a new tab)Sponsored. Affiliate link: I may earn a commission. The inclusion of Interactive Brokers’ (IBKR) name, logo or weblink is present pursuant to an advertising arrangement only. IBKR is not a contributor, reviewer, provider or sponsor of content published on this site, and is not responsible for the accuracy of any products or services discussed.
About this data. Data sourced by Tiingo (opens in a new tab). The live price is Tiingo’s real-time price, based on IEX trades and quotes; intraday charts show IEX trades, and volume figures are consolidated totals for completed sessions. Prices are split-adjusted, and total returns assume dividends are reinvested. Financials come from company filings and can lag new reports. Times are Eastern.
This page is for education, not investment advice. Past performance doesn't predict future returns. Logos provided by Logo.dev (opens in a new tab).
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